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Center for HIV/AIDS Vaccine Immunology (CHAVI)

Published on AidPage by IDILOGIC on Jun 24, 2005
Administered by:

Department of Health and Human Services, National Institutes of Health, National Institutes of Health
(see all US Federal Agencies)

Explore all postings for this grant program:
  • Original Grant - Oct 5, 2004
Applications Due:

Feb 23, 2005

total funding: $14,900,000
max award: none
min award: none
cost sharing, matching: No
number of awards: 1
type of funding: Cooperative Agreement

NIAID seeks to establish a Center for HIV/AIDS Vaccine Immunology (CHAVI) that will support intensive and highly collaborative projects addressing key immunological roadblocks to the discovery and development of a safe and effective HIV vaccine as defined by NIAID and identified by the Global HIV Vaccine Enterprise. Over the 7-year project period the research to be designed and conducted by CHAVI will address: (1) the elucidation of (a) early immunologic and virologic events after HIV-1 infection in humans, and/or (b) immune correlates for protection in animal models; (2) the systematic design and evaluation of immunogens and adjuvants eliciting persistent mucosal and/or systemic immune responses; and (3) the evaluation of vaccine candidates in early phase clinical trials. First year funding will support a CHAVI Director and the awardee institution for (1) the further development and initial implementation of a Scientific Agenda and Strategic Plan for !
all CHAVI activities; (2) the Management and Operations resources to coordinate and manage the entire range of CHAVI activities; (3) research, to be undertaken by the CHAVI Director and investigators in the CHAVI Scientific Leadership Group, focusing on: elucidation of early immunologic and virologic events after HIV infection, and/or elucidation of correlates of immune protection in non-human primate models; as well as initiating the systematic evaluation of vaccine candidates and immunization strategies to enhance mucosal immunity, potency, antigen presentation and immunogenicity; and (4) the development of scientific resources and facilities essential to implement the Scientific Agenda. Expanded funding in the second and subsequent years will support additional research and additional investigators to fully implement the CHAVI Scientific Agenda.

Who can apply:

Anyone/General Public
City Or Township Governments
County Governments
Federally Recognized Indian Tribal Governments
Independent School Districts
Minority Group
Native American Organization
Non-Government - General
Nonprofits Having A 501(C)(3) Status With The IRS, Other Than Institutions Of Higher Education
Nonprofits That Do Not Have A 501(C)(3) Status With The IRS, Other Than Institutions Of Higher Education
Other Private Institution/Organization
Private Institutions Of Higher Education
Private Nonprofit Institution/Organization (Includes Institutions Of Higher Education, Hospitals)
Profit Organization
Public And State Controlled Institutions Of Higher Education
Public Housing Authorities/Indian Housing Authorities
Quasi-Public Nonprofit Institution/Organization
Small Business (Less Than 500 Employees
Special District Governments
State (Includes District Of Columbia; Includes Institutions Of Higher Education And Hospitals)
U.S. Territories And Possessions (Includes Institutions Of Higher Education, Hospitals)

Eligible functional categories:
Funding Sources:

Allergy, Immunology and Transplantation Research
Allergy, Immunology and Transplantation Research

More Information:


If you have problems accessing the full announcement, please contact: NIH OER Webmaster

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